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Esophagitis Clinical Research


Woman suffering from esophagitis symptoms in Port Orange, FloridaAccord Clinical Research is a leader in esophagitis clinical research and actively conducts clinical trials on gastric disorders. Esophagitis can be difficult to treat and the long-term inflammation it causes can lead to the development of precancerous cells in the esophagus.  This is why esophagitis clinical research is so important here in Florida.

By conducting clinical trials on esophagitis, our research team has developed a better understanding of how this disorder develops and how best to prevent or actively treat symptoms. Through our esophagitis clinical research, we hope to improve:

  • Diagnostic procedures
  • Available medications
  • Our patients overall quality of life

Want to take an active role in esophagitis clinical research? You can fill out the form in the right hand corner of this page. A member of our staff will then contact you to discuss eligibility for an upcoming esophagitis clinical trial at our clinic in Port Orange. You can also call us at (386) 760-7272 to speak with one of our clinical trial experts.

What Is Esophagitis?

Esophagitis can be characterized as an irritation or inflammation of the tube that carries food down to the stomach from the throat, known as the esophagus. A variety of symptoms may occur as a result of esophagitis, including heartburn, sore throat, and difficulty swallowing.

Bacterial infections, viral infections, acid reflux, and side effects of some medications can all cause esophagitis. If left untreated, esophagitis can lead to a serious narrowing of the esophagus and even stomach ulcers.

The specific cause of your condition will change the outcomes of your treatment and the options you may pursue. Frequently, healthy people will improve with the correct treatment within two to four weeks. It may take more time for those with an infection or a weakened immune system to fully recover.

There are various types of esophagitis, including:

  • Eosinophilic Esophagitis – Eosinophilic esophagitis occurs when there are too many white blood cells present in the esophagus as a reaction to the body’s overt response to an irritant. The Boston Children’s Hospital reports that 1 in 10,000 children suffers from this form of esophagitis, which can present difficulties when they attempt to eat. Peanuts, beans, eggs, milk, soy, rye, wheat, and beef are all frequent trigger items, as well as pollen.
  • Drug-Induced Esophagitis – If certain medications are ingested without sufficient fluids, they may linger in the esophagus and drug-induced esophagitis may occur. These medications include antibiotics, pain relievers, bone-loss preventers, and potassium chloride.
  • Reflux Esophagitis – This form of esophagitis is commonly due to gastroesophageal reflux disease (GERD), which is a condition where the contents of the stomach, especially acids, rise up into the esophagus. Reflux esophagitis can cause chronic irritation and inflammation of the esophagus.
  • Infectious Esophagitis – This kind of esophagitis is a result of bacteria, fungi, viruses, or parasites. Though very rare, your risk is increased if your immune system has been weakened because of medications or disease. Infectious esophagitis is common in those with diabetes, HIV/AIDS, or cancer.

Risk Factors for Esophagitis

There are a number of factors that can increase your chances of developing esophagitis, including:

  • Weakened immune system because of autoimmune illnesses, such as leukemia, lymphoma, diabetes, or HIV/AIDS
  • Chemotherapy
  • Radiation therapy in the thoracic region
  • Medications meant to aid in organ transplant
  • Anti-inflammatory medications or aspirin
  • Thoracic surgery
  • A condition where the stomach pushes through the opening in the diagram between the esophagus and the stomach, known as hiatal hernia
  • Obesity
  • Alcohol and cigarette abuse
  • Chronic vomiting
  • Family history of esophagitis or sensitivity

Though the above factors may preclude you to a certain vulnerability, your chances of developing esophagitis is minimal with a healthy immune system and good lifestyle choices.

Long Term Outlook for Esophagitis

If esophagitis is left untreated, it may lead to more severe health complications with the esophagus, including:

  • Perforation of the esophagus
  • Damage to the esophagus, known as Barrett’s esophagus
  • Narrowing of the esophagus that may lead to complications while swallowing
  • Esophageal cancer

Tips for Preventing for Esophagitis

Like many bodily ailments, esophagitis may be prevented with the appropriate behavioral and health techniques. If your condition is linked to food sensitivities, begin to identify the foods that trigger a reaction and remove them from your diet.

This may include:

  • Caffeine
  • Alcohol
  • Onions
  • Garlic
  • Tomatoes
  • Citrus
  • Spicy food
  • Mint
  • Chocolate.

In general, spicy and acidic food and drink should be avoided, as should raw food. While eating, take small bites and be sure to chew food completely. Tobacco may also lead to increased inflammation of the esophagus and should be avoided.

Surgery may be required to dilate the esophagus if it has become too narrow, so speak to your doctor if you think that this may apply to you.

If the medication you take is in a solid form, avoid lying down for 30 minutes to allow it to pass through your system. Symptoms due to lingering medications may be alleviated if the medication is consumed with more water, or if there is a liquid alternative.

Esophagitis Clinical Research in Port Orange, Florida

Since we are conducting ongoing esophagitis clinical research in Port Orange, we are continuously looking for people who’d like to participate in one of our clinical trials. If you haven’t participated in a research study before, we’d recommend checking out our participant resource section. You can also call us at (386) 760-7353 if you have more specific questions.

Woman has questions about esophagitis clinical research and how it can help her symptoms

For those who are enrolled in a clinical trial, all study-related treatments and lab tests will be provided to them free of charge. Some also provide stipends to participants after the study is completed.

If you would to enroll in a clinical trial, but don’t have esophagitis, we are enrolling for other conditions as well. Otherwise, please don’t hesitate to call us at (386) 760-7353 if you have any other questions about the esophagitis clinical research we’re conducting in Port Orange.