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Overactive Bladder Clinical Research

Learn about Accord's Overactive Bladder Clinical Trials
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Man seeks overactive bladder clinical research studies in FloridaThe symptoms of an overactive bladder (OAB) can be managed with long-term treatment, but there is no comprehensive cure for this medical condition. There’s also many people that aren’t sure what’s causing their incontinence. This is why we are conducting overactive bladder clinical research in Port Orange, Florida.

Interested in learning more about overactive bladder clinical research? You can fill out the form in the right hand corner of this page. A member of our staff will then contact you to discuss upcoming research studies and your eligibility for enrollment. You can also call us at (386) 760-7272 to speak with one of our experts about the overactive bladder clinical studies in Port Orange.

What Is Overactive Bladder?

Overactive bladder is a condition that causes your bladder to suffer from poor storage function, which leads to sudden urges to urinate and potential involuntary losses of urine, otherwise known as incontinence.

OAB can cause emotional suffering as well as physical symptoms; sufferers may feel embarrassed, limit their social life, or isolate themselves from friends and family. A brief evaluation may specify the cause of your OAB and allow you to handle your symptoms.

Behavioral strategies are the foundation of managing OAB symptoms. These include fluid schedules, bladder-holding techniques, and timed voiding. If none of these mechanisms help with your symptoms, more treatment options are available.

What Causes an Overactive Bladder?

During typical urination, urine produced in the kidneys drains into the bladder, which is then passed through an opening at the bottom of the organ and flows out a tube known as the urethra. In men, the urethral opening is at the tip of the penis, but in women it is found just above the vagina.

As the bladder fills, our brain is triggered by nerve signals that indicate the need to urinate. Nerve signals coordinate the relaxation of the pelvic floor muscles and the urethral muscles, known as urinary sphincter muscles, while the muscles of the bladder contract, pushing out urine.

The above paragraphs detail normal bladder contractions. OAB happens when the muscles of the bladder perform these contractions involuntarily and often without much urine to dispose of. The need is created by the involuntary contractions. There are several reasons for OAB, which include:

  • Medications that cause rapid urine production or require fluids for consumption
  • High urine production that may be a result of poor kidney function, diabetes, or increased intake of fluids
  • Acute urinary tract infections, which can result in symptoms resembling an overactive bladder
  • Bladder abnormalities, including bladder stones or tumors
  • Constipation, previous operations for incontinence, or enlarged prostate, which may obstruct bladder outflow
  • Excessive caffeine or alcohol intake
  • Neurological disorders, including multiple sclerosis, strokes, or Parkinson’s disease
  • Declining cognitive function may make it difficult for the bladder and the brain to coordinate via nerve signals
  • Lower levels of estrogen as a result of menopause, which weakens the muscles of the bladder and the urethra
  • Pregnancy may cause sudden urges and incontinence because of pressure on the bladder and an expanded uterus
  • Incomplete urination, which may leave little space left in the bladder
  • Poor walking ability, which may hamper you if you’re unable to reach a toilet
  • Constipation

Though the above causes may indicate OAB, the specific reason is often unknown. Certain activities are known to trigger incontinence in those who suffer from symptoms, including:

  • Insufficient amounts of fluids
  • Low fiber intake
  • Constipation
  • Obesity
  • Consumption of acidic foods like citrus fruits and tomatoes
  • Excess caffeine and alcohol

Risk Factors

Certain circumstances may put a person at greater risk for overactive bladder symptoms. They include the following:

  • Age – The chances of suffering from OAB increase significantly with age, though symptoms may occur at any time. The National Association for Continence (NAFC) reports that one in five adults over 40 will suffer from OAB or chronic symptoms of frequency or urgency.
  • Gender – Women are more likely to be afflicted with symptoms of OAB than men. According to the NAFC, 85% of those suffering from OAB in America are female. This is mostly because pregnancy, menstruation, and menopause can change estrogen levels and weaken the muscles of the pelvic floor, effectively increasing the risk of difficulty with bladder function. Enlarged prostates and damage due to prostate cancer surgery may cause symptoms of OAB in men.
  • Obesity – Obesity may lead to issues with bladder function because of the pressure that excess weight puts on the organ. It can also decrease nerve activity and blood flow to the bladder, which damages control functions. For those who suffer from this risk factor, losing weight has been found to completely eliminate the symptoms.

Strategies to Cope

OAB can be a difficult ailment to live with. Advocacy support groups such as the National Association for Continence offer online resources containing information that can help those who have never experienced OAB and may connect you to those who have lived with its symptoms for many years. There are also many support groups that allow you the chance to voice concerns and ask questions regarding OAB, especially the self-care strategies essential to the management of symptoms.

Many find that educating their friends and family may help to built a network of support and reduce feelings of inadequacy or embarrassment. The condition is really quite common, and open dialogue may help you to feel more at peace with its symptoms.

Prevention

Though OAB is very common, certain lifestyle choices may reduce the risk of its occurrence, including:

  • Regular physical exercise
  • Not smoking
  • Management of chronic conditions that might contribute to overactive bladder symptoms, like diabetes
  • Limited consumption of alcohol and caffeine
  • Kegel exercises, which strengthen the pelvic floor muscles

Overactive Bladder Clinical Research in Port Orange, FL

Want to take a more active role in the overactive bladder clinical research we’re conducting in Port Orange? We’d be happy to answer any questions that you have about enrolling in a clinical trial. There’s also more information in our study participant resource section.

Doctor discusses overactive bladder clinical research with a patient

 

If you participate in an incontinence clinical trial, all study related tests and prescribed medication will be provided free of charge. Participants may also receive compensation for completing a research study at Accord Clinical Research.

Since 1998, we’ve invested a lot of resources to conduct ongoing clinical research on bladder disorders like OAB. If you are not eligible for one of our OAB clinical trials, there are other conditional studies you might qualify for. Call us today at (386) 760-7353 and our research team will find the most appropriate study to enroll you in.