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Migraine Headache Clinical Research

Learn about Accord's Migraine Headache Clinical Trials


Woman researchers migraine headache clinical research in FloridaThere is no cure for people who suffer from frequent migraines, the symptoms of which can be extremely debilitating. This is why migraine headache clinical research is so important. Our research team at Accord Clinical Research is working to improve preventative measures and treatment options by conducting migraine headache clinical trials.

Want to take an active role in migraine headache clinical research? You can fill out the form in the right hand corner of this page. A member of our staff will then contact you to discuss your eligibility for an upcoming migraine headache clinical trial in Port Orange. You can also call us at (386) 760-7272 to speak with one of our clinical trial experts.

How Do I Know if It’s a Migraine Headache?

Migraine headaches are usually identified by the intense pain they may cause, often accompanied by nausea, vomiting, and light or sound sensitivity. The enormous amount of pain caused by migraine headaches can last for hours and may only be helped by finding a dark and quiet place to lay down.

Migraines can produce early warning signs or sensory warning symptoms such as blind spots, flashing lights, or limbic tingling, known as an aura.

Medication may help reduce the occurrence and intensity of migraines if paired with self-help routines and changes in lifestyle. Consult your doctor to see if this alternative is right for you.

What Causes Migraines?

Two factors are understood to be connected to migraines: environment and genetics. Migraines may also be induced by interactions between the brain and trigeminal nerve, a major pain pathway.

Some migraine headache clinical research has linked brain chemicals like serotonin to attacks as well. Serotonin levels appear to drop during migraine episodes, which may signal the trigeminal nerve to release neuropeptides. Neuropeptides can cause headache pain as they travel to the meninges, the brain’s outer covering.

Common Migraine Triggers

  • Foods – Processed foods, aged cheeses and salty foods can trigger migraines, as can skipping meals or fasting.
  • Food Additives – Preservatives like monosodium glutamate and sweetener aspartame, both found in many foods, may trigger migraines.
  • Drinks – Caffeinated beverages as well as alcohol, particularly wine, may induce migraines.
    Stress
  • Sensory Stimuli – Loud sounds, bright lights, sun glare and unusual smells, such as smoke, perfume and paint thinner, can also induce migraines.
  • Weather & Environment Fluctuations – Changes in pressure or weather can cause migraines.
  • Physical Factors – Physical exertion, including sexual activity, may induce migraines.
  • Sleep Pattern Fluctuations – Unstable sleep patterns may bring on migraines.
  • Medications – While some specific medications may help, oral contraceptives and vasodilators may trigger migraine episodes.
  • Hormonal Fluctuations in Women – Fluctuations in estrogen levels can bring upon migraines, as they often drop during or before periods.

Risk Factors for Migraines

There are multiple factors that can increase risk for migraines. Below is a list of migraine headache risk factors and an explanation of each:

  • Family Medical History – Susceptibility has a high correlation with genetics. Up to 90% of those who suffer from migraines have a family history of attacks. Presence of habitual migraines in one of both of your parents increases your risk of migraine attacks.
  • Age – The onset of migraines may occur at any age, though most people experience it first in adolescence and no later than 40.
  • Sex (Gender) – Headaches tend to affect boys more than girls during childhood, but by adulthood, women are three times more likely to be afflicted by migraines.
  • Hormonal Changes – It’s common for women to have headaches before or soon after their period. Incidences may also change during pregnancy or menopause, though migraines tend to alleviate after menopause. For many women, migraines improved or stopped during later stages of pregnancy, though some do claim that onset began during pregnancy.

Difference Between Migraines and Headaches

Headaches are common, but most people still don’t know how to distinguish between that and a migraine. In migraines, the blood vessels constrict and dilate, causing painful pulsations. The pain can range in intensity and duration, lasting anywhere from four hours to a week.

The following symptoms may indicate a migraine and not just a normal headache:

  • Moderate to severe pain that can shift to different parts of the head or affect it all at once.
  • Light, noise, or odor sensitivity
  • Nausea or vomiting
  • Upset stomach or abdominal pain
  • Loss of appetite
  • Temperature fluctuations
  • Paleness
  • Dizziness
  • Fever
  • Fatigue
  • Bright lights or flashing dots, wavy lines, blind spots, which are signs of an aura

Best Way to Prevent Migraines

By making certain lifestyle changes, you can prevent more migraine headaches.  Combining these steps with migraine medication can be even more effective. The list below identifies other suggestions that can help those dealing with migraines:

  • Reduce caffeine and alcohol intake
  • Avoid tobacco
  • Establish regular sleep patterns
  • Exercise regularly – Aerobic exercises can reduce stress and prevent migraine headaches.
  • Reduce the effects of estrogen – Women with migraines may want to avoid or reduce medications with estrogen, such as birth control pills and hormone replacement therapy.

Remember to record your migraine headache triggers. This can be accomplished more effectively by keeping a headache diary. Learn from the past and avoid foods or odors that trigger your migraine symptoms.

Migraine Headache Clinical Research in Port Orange, FL

Interested in the migraine headache clinical research we’re conducting in Port Orange? We’d be happy to answer any questions that you have about participating in a study. You can also find a lot of helpful information in our study participant resource section.

Doctor discusses migraine headache clinical research with a patient

If you do participate in a migraine clinical trial, all study related tests and prescribed medication are provided free of charge. Participants may also receive compensation for completing a clinical study at Accord Clinical Research.

Our clinic in Port Orange has invested a lot of resources in conducting clinical research on migraine headaches. Still, you might not be eligible for one of our migraine headache clinical trials. If you are interested in helping us advance modern medicine, call us today at (386) 760-7353 and our research team will find the most appropriate study to enroll you in.